Alkaloids 1 Quiz Questions PDF

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Alkaloids 1 – Quiz Questions History of Alkaloids:

● Which alkaloid was isolated from opium as the first crude drug? a) Morphine b) Nicotine c) Cocaine d) Caffeine

● Who first coined the name “Alkaloids”? a) S.W. Pelletier b) Fredrich Sertürner c) Karl Fredrich Wilhelm Meissner d) Joseph Caventou

● An alkaloid is defined as a “cyclic organic compound containing nitrogen in a ______ oxidation state”. a) Positive b) Neutral c) Negative

Structure and Classification of Alkaloids:

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The three types of alkaloids are: a) True alkaloids, false alkaloids and neutral alkaloids b) Proto alkaloids, non-proto alkaloids and pseudo alkaloids c) True alkaloids, proto alkaloids and pseudo alkaloids d) Proto alkaloids, pseudo alkaloids and false alkaloids

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Which of the following is the common functional group in an alkaloid structure? a) Amine b) Carboxyl acid c) Amide d) Ketone

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The name alkaloid is taken from the word “alkaline”, which is refer to substances with a pH of: a) Equal to 7 b) Greater than 7 c) Less than 7 d) Equal to 14

The Biosynthesis of alkaloids: 

What is one of the key reactions in the biosynthesis of alkaloids: a) Mannich reaction b) Williamson Ether c) Diels Alder reaction d) Grignard reaction

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The Mannich reaction involves the ____________ addition of an amine group. a) electrophilic b) nucleophilic c) electrophilic aromatic d) both A and B

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The Schiff Base can act as which of the following?

a) electrophile b) nucleophile c) leaving group d) A and C

Alkaloidal Mode of Action:

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Which of the followings is the name of the enzyme that catalyzes the hydrolysis of acetyl groups? a) kinase b) esterase c) dehydrogenase d) carboxylase

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Which of the following methods of administration provides the quickest onset of a drug? a) insufflation b) inhalation c) intravenous d) oral administration

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After passing through the Blood Brain Barrier heroin is converted into _________ before binding to an opioid receptor. a) caffeine b) codeine c) ephedrine d) morphine

Substance Abuse of alkaloids:

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Which one of these characteristics has a strong correlation for drug abuse? a) Gender b) Weight c) Income d) None of the Above

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In the United States, the amount of deaths from drug overdosing has: a) Stayed Consistent b) Decreased c) Increased d) None of the above

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What effects does an individual's amount of education have on their likelihood of abusing drugs? a) They are more likely to abuse drugs b) They are less likely to abuse drugs c) There is no significant correlation d) None of the above

Ergot alkaloids:

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The chirality of the C-5 carbon in an ergot alkaloid is _____. This configuration is ___________ among alkaloids. a) S; consistent b) R; different depending on the precursor amino acid

c) R; consistent d) S; not consistent

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What are the three ways of systematically naming ergot alkaloids? a) cyclic systems, full peptidic systems, IUPAC b) plants, effects, belladonna c) IUPAC, cyclic systems, ergoline d) full peptidic systems, ergoline, effects

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Which of the following effects is NOT directly related to ergot alkaloids and their derivatives? a) can cause hallucinations b) contract uterine lining during childbirth c) potential for poisoning d) enlarged blood vessels in lower limbs...