Direct Gene Activation- Worksheet PDF

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Endocrine System: Mechanism of Hormone Action: Direct Gene Activation 1. a. Lipid-soluble hormones such as _steroid ________ and _thyroid _________ hormones bind to receptors located __inside the cell_____________. b. Once the hormone binds to the receptor, the __chaperone________ dissociates from the receptor complex. c. The hormone–receptor complexes act as _transcription factors _______. d. The receptor–hormone complex then binds to _Hormone Response Elements on DNA_____. e. The mRNA produces __enzymes _________ that catalyze biochemical reactions in the cell. 2. Cortisol is classified as a/an _steroid__ hormone. Name four major actions of cortisol. 1. Gluconeogenesis/Gycogenolysis _

3. __Vasoconstriction ___________

2. _Lipolysis & protein breakdown __

4. __Inhibition of inflammation & immune response

These actions are important for the stress response. 3. The main function of thyroid hormones is: __regulation of metabolic rate _______. Three other specific functions include: 1. _increases BMR_______ 2. _alters car, lipid and protein metabolism ______ 3. _growth ____________________...