Exam 1 2021 Practice Exam Version 2: Unit 1 OpenStax Microbiology PDF

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Exam 1 2021 Practice Exam Version 2: Unit 1 OpenStax Microbiology...

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Bio 215: Exam 1, Fall 2019. 100 pts total.

Version 2

Directions: Write answers to the matching section and short answers on the BACK of the Scantron sheet. Put answers to multiple choice and true/false questions on the Scantron bubble sheet. PUT YOUR NAME & VERSION NUMBER ON THE SCANTRON SHEET!!! Section 1: Multiple Choice (50 pts) Each question is 2 pts. 1. A protein/glycoprotein outer layer that seems to help cells withstand osmotic pressure and interact with the immune system is the: a. Glycocalyx c. capsule b. S-layer d. slime layer 2. Which of the following is used in bacterial metabolism, containing the protein RuBiSCO? a. Magnetosome c. carboxysome b. Plasmid d. vacuole 3. How do bacterial and eukaryotic ribosomes differ? a. Bacteria have more rRNA and fewer proteins b. Bacteria have less rRNA and fewer proteins c. Bacteria have more rRNA and more proteins d. Bacteria have more rRNA, and no proteins. 4. Which of these structures can be used to donate DNA to another bacterial cell, in a process known as conjugation? a. Flagella b. Fimbriae c. Pili d. Integral membrane proteins 5. Which of the following can make endospores? a. All bacteria b. Only some Gram+ bacteria c. Only some Gram- bacteria d. Only peritrichous bacteria 6. Each subunit of a viral protein coating is called a _____. a. Capsid b. Capsomere c. Envelope d. Integral membrane coating

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7. After lysogenic virus DNA is excised from its host chromosome, what step can occur? a. Biosynthesis c. Lysis of the host cell b. Maturation/Assembly d. Insertion 8. Which of the following is a malformed protein that can cause brain diseases? a. Prion c. virusoid b. Viroid d. virus 9. Fungal filaments can be strengthened by crosswalls known as ______. a. Conidia c. Hyphae b. Conidiophores d. Septa 10. The ploidy level (n+n) in an Ascomycete is referred to as the _____. a. Diploid c. haploid b. Dikaryon d. yeast 11. Which of the following structures is found in BOTH Gram- and Gram+ bacteria? a. Envelope c. Periplasm b. Outer membrane d. Lipopolysaccharide 12. NAM and NAG are found in the bacterial _______ a. Plasma membrane c. cell wall b. Slime layer d. magnetosome 13. A disease gained due to a medical procedure is known as a _____ disease. a. iatrogenic b. nosocomial c. zoonotic d. chronic 14. Which of the following connects the plasma membrane and layers of the cell wall in Gram+ bacteria? a. Teichoic acids b. Murein lipoprotein c. Lipopolysaccharides d. D-amino acids 15. Which of the following GI bacteria does not typically have virulence factors letting it invade the bloodstream &/or intestinal epithelial cells? a. Listeria monocytogenes c. Shigella b. Escherichia coli d. Salmonella

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16. What type of worm is Taenia? a. Cestode b. Nematode c. Trematode d. None of the above 17. What is NOT TRUE about Helicobacter pylori? a. Found in many asymptomatic patients b. Can cause stomach ulcers c. Uses urease to protect itself from stomach acid d. Symptoms include weight gain and diarrhea. 18. Which of the following viruses is enveloped? a. Mumps c. Rotavirus b. Norwalk virus d. none of the above 19. Which of the following fungal cell structures would make the best antibiotic target in medicine? a. Ribosome c. Cell membrane b. Mitochondria d. Nucleus 20. Which fungi can produce flagella? a. Ascomycota b. Basidiomycota c. Chytridiomycota d. Zygomycota 21. Candida albicans, like other dimorphic fungi, can do what (by definition)? a. Infect multiple body parts (GI & female reproductive tract) b. Infect multiple hosts (animals and humans) c. Grow as two sexes (+ and -) d. Switch between growth forms (yeast and filamentous) 22. Examine the worm life cycle on the coversheet. What is true about this worm’s life cycle? It is ______, meaning _________. A. Dioecious; it has two separate sexes B. Dioecious; it has testes and ovaries in the same body C. Hermaphroditic; it has two separate sexes D. Hermaphroditic; it has testes and ovaries in the same body

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23. Examine the worm life cycle on the coversheet. What is true about its host? Humans are its ____ host; this means the worm can _____ in a human. a. Definitive; grow b. Definitive; reproduce c. Intermediate; grow d. Intermediate; reproduce 24. Examine the bacterial cell wall diagram on the coversheet. Name whether it is Gram+ or Gram-, along with the main component in its cell wall. a. Gram- ; chitin b. Gram- ; peptidoglycan c. Gram+ ; chitin d. Gram+ ; peptidoglycan 25. Examine the bacterial cells on the coversheet. What the shape of the cells? a. bacillus c. spirillus b. coccus d. vibrio Section 2: True/False (10 pts) Each question worth 2 pts. Scantron: A = True, B = False. 26. Calcium and dipicolinic acid are used to form the thick cortex of an endospore. FALSE 27. Under the classic Koch’s postulates, the causal agent of a disease should cause disease in 50% of healthy host organisms. FALSE 28. An organism with a LOW ID50 is MORE infectious than one with a high ID50 . TRUE 29. A patient with a latent infection is not infectious during periods of latency. TRUE 30. A symptom is observable to a medical professional, while a sign is only sensed by the patient. FALSE For the following questions, use the BACK of your Scantron sheet to record your answers. Section 3: Matching (30 pts) K. Neisseria gonorrhoeae F. Enterobius vermicularis A. Ascaris lumbricoides L. Streptococcus mutans G. Giardia lamblia B. Candida albicans M. Treponema pallidum H. Hepatitis C. Chlamydia trachomatis N. Trichinella I. Herpes simplex virus 2 D. Cryptosporidium parvum O. Trichomonas vaginalis J. Human papilloma virus E. Entamoeba histolytica 1. Multiple viruses can cause this inflammation of the liver, which can be fatal if left untreated. Depending on the particular cause, it could be transmitted through food, water, surfaces, or bodily fluids. H 2. This enveloped, dsDNA virus can cause genital sores, but can also be found on other mucosal surfaces if transmitted via sex. I 4

3. This non-enveloped dsDNA virus can cause genital warts, which can lead to cervical cancer. J 4. A fungus that is a common commensal in the vagina but can cause yeast infectious after some disruption such as antibiotic therapy. B 5. This flagellated protist can cause sexually transmitted disease in men and women, although men are likely to be asymptomatic. O 6. The most common waterborne illness in the US, it is a flagellated protist causing recurrent diarrhea and greasy stools. G 7. This Gram+ coccus is a top cause of tooth decay, being found in dental plaque and tartar. L 8. This Gram- coccus can cause a common STI and may be difficult to treat due to widespread antibiotic resistance. Many patients are asymptomatic, but some experience severe complications, such as bacteremia, endocarditis, arthritis, and meningitis. K 9. This Gram- spirochaete causes syphilis, a disease with multiple stages that can end in blindness, dementia, and death. M 10. This Gram- bacterium causes a common STI, can be coccoid or rod-shaped, and lacks a cell wall. It is an intracellular pathogen that invades and infects host cells. C 11. A flagellated protist that is commonly gained from swimming pools, as its sporozoites can survive chlorinated water. Infections can occur through contact with infected livestock or contaminated food or water. D 12. An amoeboid protist that can cause bloody diarrhea and, in severe cases, liver abscesses. E 13. A nematode (pinworm) that lay eggs around the anus and causes severe itching. F 14. A roundworm that can cause dangerous blockages of the small intestine and may need surgical removal. A 15. A nematode that can cause cysts in pork and some game animals and can infect humans who eat undercooked, infested meat. N Section 4: Short Answer (10 pts) 1. 6 pts. List the 5 stages of disease progression. Explain what each stage entails for the patient. a. Incubation; no signs/symptoms b. Prodromal; vague signs/symptoms, most contagious c. Illness; clear signs/symptoms d. Decline; patient starts getting better e. Convalescence; cleared infection, may be lasting effects 2. 4 pts. Name 2 defensive features of either the digestive or genitourinary (aka urogenital) system. State why each feature is helpful in preventing infection. GU: urinating/flushing, mucous Digestive: stomach acid, mucous membranes Section 5: Extra Credit (4 pts) 5

A child experiencing dysentery is brought to the hospital in a very weak state. The parents request fast antibiotic treatment. Explain 1) What dysentery is, 2) list 2 possible causes of dysentery, and 3) explain 1 reason antibiotic therapy may be a bad idea

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