Med Map - Prilosec (omeprazole) PDF

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Summary

Medication Map ATI Prilosec (omeprazole)...

Description

ACTIVE LEARNING TEMPLATE:

Medication

ST UDENT NAME _____________________________________

Prilosec (omeprazole) Proton pump inhibitor and antiulcer CATEGORY CLASS ______________________________________________________________________

MEDICATION __________________________________________________________________________

REVIEW MODULE CHAPTER ___________

PURPOSE OF MEDICATION

Expected Pharmacological Action Omeprazole interferes with gastric acid secretion by inhibiting the hydrogen potassium adenosine triphosphatase (H+ K+ -ATPase) enzyme system, or proton pump, in gastric parietal cells.

Therapeutic Use

To treat symptomatic gastreophageal reflux disease

Complications CNS: Agitation, asthenia, dizziness, drowsiness, fatigue, fever, headache, malaise, psychic disturbance, somnolence CV: Chest pain, hypertension, peripheral edema EENT: Anterior ischemic optic neuropathy, optic atrophy or neuritis, otitis media, stomatitis ENDO: Hypoglycemia GI: Abdominal pain, acid regurgitation, constipation, diarrhea, Clostridium

Medication Administration

DELAYED-RELEASE CAPSULES, DELAYEDRELEASE TABLETS, DELAYED-RELEASE ORAL SUSPENSION

Contraindications/Precautions

Concurrent therapy with rilpivirine-containing products; hypersensitivity to omeprazole, substituted benzimidazoles, or their components

Interactions atazanavir, nelfinavir, rilpivirine: Decreased plasma levels of these agents; promote drug resistance to these drugs cilostazol diazepam, digoxin, phenytoin, tacrolimus: Increased exposure of these drugs citalopram: Increased exposure of citalopram leading to increased risk of QT prolongation clopidogrel: Reduced effectiveness of clopidogrel CYP2C19 or CYP3A4 inducers such as rifampin, St. John’s Wort: Decreased exposure of omeprazole CYP2C19 or CYP3A4 inhibitors such as voriconazole: Increased exposure of omeprazole dasatinib, erlotinib, iron salts, itraconazole, ketoconazole, mycophenolate mofetil, nilotinib: Reduced absorption of these drugs methotrexate: Possibly delayed methotrexate elimination and increased risk of toxicity saquinavir: Increased plasma saquinavir level and risk of toxicity St. John’s wort, rifampin: Decreased plasma omeprazole level warfarin: Possibly increased risk of abnormal bleeding

Evaluation of Medication Effectiveness

After evaluating this medication I believe that it is very effective because it is easier to teach patients how to effectively and correctly take medication

ACTIVE LEARNING TEMPLATES

Nursing Interventions Give omeprazole before meals, preferably in the morning for once-daily dosing. If needed, also give an antacid, as prescribed. If needed, open capsule and sprinkle entericcoated granules on applesauce or yogurt or mix with water or acidic fruit juice, such as apple or cranberry juice. Give immediately. Give drug via NG tube, when needed by mixing granules in acidic juice, because enteric coating dissolves in alkaline pH, or using the delayedrelease oral suspension form by mixing with water.

Client Education Tell patient to take drug before eating —usually before breakfast—and to swallow delayed-release capsules or tablets whole. If needed, patient may sprinkle contents of capsule onto 1 tablespoon of applesauce and swallow immediately without chewing pellets. Tell him to follow with a glass of cool water and not to keep any leftover mixture. THERAPEU TIC P ROCEDURE

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