Medication - Glyburide PDF

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Quick guide on glyburide...

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ACTIVE LEARNING TEMPLATE:

Medication

STUDENT NAME _____________________________________

(DiaBeta) MEDICATION glyburide __________________________________________________________________________

REVIEW MODULE CHAPTER ___________

; sulfonylureas CATEGORY CLASS Antidiabetics ______________________________________________________________________ PURPOSE OF MEDICATION

Expected Pharmacological Action Lowers blood sugar by stimulating the release of insulin from the pancreas and increasing the sensitivity to insulin at receptor sites. May also decrease hepatic glucose production.

Therapeutic Use PO Control of blood sugar in type 2 diabetes mellitus when diet therapy fails. Requires some pancreatic function.

Complications CNS: dizziness, drowsiness, headache, weakness, Derm: ERYTHEMA MULTIFORME, photosensitivity, exfoliative dermatitis, rash, Endo: hypoglycemia, GI: constipation, cramps, diarrhea, drug-induced hepatitis, dyspepsia, appetite, nausea, vomiting

Medication Administration PO (Adults): DiaBeta (non-micronized)– 2.5– 5 mg once daily initially (range 1.25– 20 mg/day).

Contraindications/Precautions Hypersensitivity, Hypersensitivity to sulfonamides (cross-sensitivity may occur), Type 1 diabetes, Diabetic coma or ketoacidosis, Concurrent use of bosentan

Interactions Increased risk of elevated liver enzymes when used with bosentan (avoid concurrent use). Ingestion of alcohol may result in disulfiram-like reaction. Effectiveness may be decreased by concurrent use of diuratics, corticosteroids, phonothiazines, oral contraceptives, estrogens, thyroid preparations, phenytoin, nicotinic acid and isoniazid.

Evaluation of Medication Effectiveness Control of blood glucose levels without the appearance of hypoglycemic or hyperglycemic episodes.

ACTIVE LEARNING TEMPLATES

Nursing Interventions Observe for signs and symptoms of hypoglycemic reactions (sweating, hunger, weakness, dizziness, tremor, tachycardia, anxiety). Patients on concurrent beta-blocker therapy may have very subtle signs and symptoms of hypoglycemia.

Client Education Instruct patient to take medication at same time each day. Take missed doses as soon as remembered unless almost time for next dose. Do not take if unable to eat. Explain to patient that this medication controls hyperglycemia but does not cure diabetes. Therapy is long term.

THERAPEUTIC PROCEDURE

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