Medication Memantine - ati template PDF

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ACTIVE LEARNING TEMPLATE:

Medication

Peters STUDENT NAME Kayla _____________________________________ MEDICATION Memantine __________________________________________________________________________

REVIEW MODULE CHAPTER ___________

antagonist CATEGORY CLASS N-methyl-D-aspartate ______________________________________________________________________ PURPOSE OF MEDICATION

Expected Pharmacological Action Binds to CNS N-methyl-D-aspartate (NMDA) receptor sites, preventing binding of glutamate, an excitatory neurotransmitter

Therapeutic Use Decreased symptoms of dementia/cognitive decline. Does not slow progression. Cognitive enhancement. Does not cure disease.

Complications Dizziness, fatigue, headache, sedation, hypertension, rash, diarrhea, weight gain, urinary frequency, anemia

Medication Administration PO (Adults): Immediate-release—5 mg once daily initially,increase at weekly intervals to 10 mg/day (5 mg twice daily), then 15 mg/day (5 mg once daily, 10 mg once daily as separate doses), then to target dose of 20 mg/day (10 mg twice daily); Extendedrelease—7 mg once daily, increase at weekly intervals by 7 mg/day to target dose of 28 mg once daily

Contraindications/Precautions -Hypersensitivity -Severe renal impairment ( increase dose); Concurrent use of other NMDA antagonists (amantadine, rimantadine, ketamine, dextromethorphan); Concurrent use of drugs or diets that cause alkaline urine

Interactions Medications that increase urine pH (e.g. carbonic anhydrase inhibitors,sodium bicarbonate) may decrease excretion and increase blood levels.

Nursing Interventions -Dose increases should occur no more frequently than weekly - PO:May be administered without regard to food. -Administer oral solution using syringe provided. Do not dilute or mix with other fluids. -Swallow extended release capsules whole; do not crush, chew, or divide. Capsules may be opened, sprinkled on applesauce, and swallowed. Entire contents of each capsule should be consumed; do not divide dose

Client Education Evaluation of Medication Effectiveness Improvement in neurocognitive decline (memory, attention, reasoning, language, ability to perform simple tasks) in patients with Alzheimer’ s disease.

ACTIVE LEARNING TEMPLATES

-Instruct patient and caregiver on how and when to administer memantine and how to titrate dose. Take missed doses as soon as remembered but not just before next dose; do not double doses. Advise patient and caregiver to read Patient Instructionssheet. -Caution patient and caregiver that memantine may cause dizziness. -Advise patient and caregiver to notify health care professional of all Rx or OTC medications, vitamins, or herbal products being taken

THERAPEUTIC PROCEDURE

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