Medication temp Piperacillin:Tazobactam PDF

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ACTIVE LEARNING TEMPLATE:

Medication

Mcbean STUDENT NAME Alliyah _____________________________________ MEDICATION Piperacillin/Tozabectan __________________________________________________________________________ REVIEW MODULE CHAPTER ___________

Pencillin - beta lactmase inhibitors CATEGORY CLASS Extended-Spectrum ______________________________________________________________________ PURPOSE OF MEDICATION

Expected Pharmacological Action Inhibits cell wall synthesis during multiplication Therapeutic class: Antibiotic

Therapeutic Use a combination of penicllin antibiotic that is used to treat many different infections caused by bacteria, such as stomach and skin infections, pneumonia and severe vaginal infection

Complications CNS: headahce, insomnia, fever, seizures, agitation, anxiety, dizziness, pain. CV: arrhythmia, chest pain, edema, HTN, tachycardia. EENT: rhinitis. GI: diarrhea, constipation, nausea, pseudomembranous colitis, abdominal pain, dyspepsia, stool changes, vomiting, oral candidiasis. GU: candidiasis, interstial nephritis. Hematologic: leukopenia, neutropenia, thrombocytopenia, anemia, eosinophilia, dyspnea, puritus, rash

Medication Administration Before giving drug ask patient about alleric reactions or penicillins, cephalosporings, or beta-lactamase inhibitors IV reconstitute each gram with 5 mLof dilutent Shake until dissolve and further dilute to 50 to 150 mL before infusion. Infuse over at least 30 min

Contraindications/Precautions -Contraindicated in patients with a history of allergic reactions to any penicillins, cephalosporins or B-lactamase -Use cautiously in patients with bleeding tendencies, uremia, hypokalemia and allergies to other drugs

Interactions Aminoglycosidas: penicillins may decrease serum concentration of aminoglycosides, anticoagulants, heparin: may prolong effectiveness and increase risk of bleeding. Monitor PT and INR closely; Hormonal Contraceptives: may decrease contracenptive effectiveness. Adivse using another form of contraceptives; Live-virus vaccines: may decrease vaccine effectivess. Dont use together; Methotrexare: may increase risk of methotrexate toxicit. Probenecid: may increase piperacillin level; Vancomycin: may increase nephrotoxicity.; Vecuronium: may prolong neuromuscular blockade

Evaluation of Medication Effectiveness -Patients WBC reach a normal level -Decrease swelling and redness -Decrease pain

ACTIVE LEARNING TEMPLATES

Nursing Interventions -If rash develops monitor patients closely and discontinue if lesions progresses -Monitor patients sodium intake and electrolyte levels -Monitor hematologic and coagulation parameters

Client Education Tell the patient to report advers reactions promptly Tell patient to report discomfort at the IV site...