Pancrelipase - med PDF

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Summary

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Description

ACTIVE LEARNING TEMPLATE

Medication NAME

CONTENT

REVIEW MODULE CHAPTER _

TOPIC DESCRIPTOR MEDICATION _pancrelipase

Contains EXPECTED PHARMACOLOGICAL ACTION:

lipolytic, amylolytic, and proteolytic activity

Therapeutic Uses

Increased digestion of fats, carbohydrates, and proteins in the GI tract.

Adverse Effects

Nursing Interventions

EENT: nasal stuffiness. Resp: dyspnea, shortness of breath, wheezing. GI: FIBROSING COLONOPATHY (high doses only), abdominal pain (high doses only), diarrhea, nausea, stomach cramps, oral irritation. GU: hematuria. Derm: hives, rash. Metab: hyperuricemia.Misc:allergic reactions

Contraindications

Assess patient’ s nutritional status (height, weight, skin-fold thickness, arm muscle circumference, and lab values) prior to and periodically throughout therapy. Monitor stools for high fat content

Hypersensitivity to hog proteins. Gout, renal impairment, or hyperuricemia Client Education Instruct patient not to chew tablets and to swallow them quickly with plenty of liquid to prevent mouth and throat irritation. Sit upright to enhance swallowing. Eating immediately after taking medication helps further ensure that the medication is swallowed and does not remain in contact with mouth and esophagus for a prolonged period.

Medication/Food Interactions

Antacids (calcium carbonate or magnesium hydroxide) may decrease effectiveness of pancrelipase

Evaluation of Medication Effectiveness

Medication Administration

PO (Adults and Children 4 yr): Initiate with 500 lipase units/kg/meal; dose should be adjusted based on weight, clinical symptoms, and stool fat content

Improved nutritional status in patients with pancreatic insufficiency. Normalization of stools in patients with steatorrhea

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