Syllabus - PGY 300 2020 Fall Final Version Updated Exam Schedule PDF

Preview

Summary

rubric
...

Description

August 13, 2020

PGY 300: Human Physiology Fall 2020 PGY300 Human Physiology is a one semester undergraduate course designed to prepare students planning on careers in Nursing, Exercise Science, or other allied health professions. It carries four units of credit and four lecture hours per week. It is a prerequisite for the UB Schools of Nursing and Exercise Science. It explores the basic functions and mechanisms of the primary organ-systems of the human body in health and disease. These include the Nervous, Cardiovascular, Respiratory, Gastrointestinal, Renal, and Endocrine systems. These systems will be studied at the organ, tissue, and cellular levels of organization. Detailed learning objectives for each lecture can be found in the last section of this syllabus. Assessment of learning these objectives will be by a multiple choice exam given at the end of each organ system section. All lecture material is available on UBlearns. The prerequisite for PGY 300 is a grade of C or higher in ANA 113 or BIO 200 or CHE 101 or ES 207. The pages that follow contain the information needed to make this course a manageable challenge. We will be ONLINE this semester so READ CAREFULLY! Course Coordinator:

Dr. Randall L. Hudson Department of Physiology and Biophysics 3102 JSMBS [email protected]

Schedule:

M and F 1:50- 2:40 PM W 1:50 – 3:50 PM Remote instruction and exams. Instructors will schedule Zoom office hours during scheduled class times and by appointment. The student’s computer MUST be compatible with Respondus Lockdown Browser and Respondus Monitor (Windows 10, 8, or 7; Mac OSX10.10 or higher operating systems). Computers must have a WEBCAM and a microphone (most newer laptops have these built in). Chromebooks do not work. For more information see

Office Hours: Required Hardware and Software:

http://www.buffalo.edu/ubit/service-guides/teachingtechnology/learning-resources-forstudents/ublearns/respondus.html

A reliable internet connection and a UB photo ID.

PGY 300 2020 Fall 1

August 13, 2020

Student Responsibility: Students are responsible for mastering the material presented by the participating faculty. Concerns regarding factual errors of ancillary material (e.g., miss-keyed practice or old exams) must be brought to our attention before the exam and not after. Memorizing a miss-keyed choice is not an acceptable excuse for failure to understand the material well enough to recognize a typographical error. UB’s Academic Integrity policy: “The university has a responsibility to promote academic honesty and integrity and to develop procedures to deal effectively with instances of academic dishonesty.” Refer to the student handbook for more detail information at http://intranet.sdm.buffalo.edu/student/handbook/. UB’s Students Needing Special Accommodations: If you have any condition, such as a physical or learning disability, which will make it difficult for you to carry out the course work as outlined, or requires extended time on examinations, notify the Course Coordinator during the FIRST TWO WEEKS of the course to discuss appropriate arrangements and/or reasonable accommodations. You will need to be approved by the Office of Accessibility Resources. They are located at 25 Capen Hall, (716) 645-2608,

http://www.buffalo.edu/equity/obtaining-assistance/obtainingaccommodations/disability-accommodations.html UB Student-Athletes: Student’s participating in UB NCAA sports need to notify the Course Coordinator of any travel conflicts with exam dates so that arrangements can be made with your coach. . This must be done as soon as you are aware of the conflict, preferably in the first week of the semester.

PGY 300 2020 Fall 2

August 13, 2020

Course Information 1) Faculty contact information.

Dr. R. Hudson **

Dr. M. Slaughter Dr. B. Weil

Dr. W. Hofmann

Dr. M. Morales

Physiology and Biophysics Office

Office Jacobs School of Medicine, Room 3203 955 Main St. 560 Biomedical Research Building Jacobs School of Medicine, Room 3112 or 7030H CTRC Jacobs School of Medicine, Room 4132 955 Main St. Jacobs School of Medicine, Room 4156 955 Main St. Jacobs School of Medicine, Room 3102 955 Main St.

Phone 829-6286

email [email protected]

829-3240

[email protected]

829-3599

[email protected]

829-3290

[email protected]

829-3965

[email protected]

829-2738

** Course Coordinator; to whom all administrative questions should be addressed. Office Hours: By appointment. 2) PGY300 has four online video instructional hours per week, for a total of 57 hours. There are six 50-minute section exams, no recitation, no laboratory, no outside assignments, and no extra credit. 3) The course is divided into six sections; Neurophysiology, Cardiovascular, Respiratory, Renal, GI, and Endocrinology. Section six (Endocrinology) will be taken during finals week. 4) Online instruction will be presented by recorded video (Panopto, available through UBlearns). 5) Scheduled class times are: M & F (1:50 - 2:40 pm), W (1:50 - 3:50 pm). Students are expected to be available online for these days and times should the need arise to reschedule an exam due to unforeseen problems. There is no Recitation or Laboratory. 6) It is the student’s responsibility to keep up with the online video schedule. Online instruction requires an additional level of organization on the part of the student.

PGY 300 2020 Fall 3

August 13, 2020 7) Required Text: Human Physiology: An Integrative Approach by D. Silverthorn, Eighth Edition. 2016. Pearson Education Inc. ISBN 978-0-13-460519-7. (7th edition is acceptable). Both the hardcopy or the e-version are acceptable. The international edition is not acceptable. None of the ancillary material (i.e., workbook, CD, etc.) are required (or needed).

8) UBlearns - PGY300 Course Site Available only to students registered in PGY300. Accessed via the URL < https://UBlearns.buffalo.edu > Lecture slides for each section can be found under Course Documents. Class Announcements will be made through UBlearns. Students are responsible for checking this site in a timely fashion. e. Grades will be posted via the UBlearns grade book.

a. b. c. d.

9) PGY 300 is online this semester. a. Video access is via UBlearns. Login to the UBlearns/PGY300 page and you will find a button on the left hand panel labeled Classroom Recordings. Click on this button and then the Recorded Lectures link to launch Panopto. b. It is the student’s responsibility to become familiar with the technical demands of online instruction and exams. Do not wait until the last minute to master the technical demands (i.e., hardware, software, internet connection). 10) Dropping this course is the student’s responsibility. We cannot do this for you. a. Last day to DROP without financial liability is September 8, 2020 b. Last day to DROP with a grade of “R” is November 13, 2020 11) Examination Policies a. There will be six online section exams. • Respondus Lockdown Browser is REQUIRED. • Respondus Monitor is REQUIRED. b. NO OTHER ELECTRONIC DEVICES are needed or permitted during any examination. • The use of any device other than the Lockdown Browser to access information relevant to the exam is considered cheating. • These devices include cell phones, second computing devices, calculators, etc. • The penalty for the use of such a device is a letter grade of F for the course and referral to the Office of Judicial Affairs. c. All students must present a valid UB photo ID at each exam to the Respondus Monitor program to begin the exam. d. There are six sections to the course: Cardiovascular, Neurophysiology, Respiration, Renal, GI, and Endocrinology. The first five sections will be tested independently on

PGY 300 2020 Fall 4

August 13, 2020 the dates shown below. The sixth section, Endocrinology, will be examined during finals week. e. There are NO MAKEUP exams in PGY300. f. Repeat: there are NO MAKEUP exams in PGY 300. g. Missing three or more section exams for any reason will result in a course grade of ‘F’. h. Students will receive via email their exam score, the exam key, and their correct and incorrect choices as soon as the exam has been graded and approved by the faculty. This can take 2-5 days. i. Challenges to exam results must be made within 3 days of the email posting of the results. j. The exams, scores, and statistics will be posted on UBlearns student grade book after the challenge period. These scores are final and no further challenges will be considered.

PGY 300 2020 Fall 5

August 13, 2020 12) Grading Policies. a. Course grade is the sum of the HIGHEST FOUR of the first five section exams plus the Final Exam. b. The Final Exam will be the Endocrinology section exam (33 points; 33 questions at one point per question). c. The Final Exam is NOT optional.

• Example of Course Grade Calculation. A student scored the following on each of the exams: Exam 1, 22 points -> 22 Exam 2, missed, out sick discard (it is the lowest of the first 5 exams) Exam 3, 33 points -> 33 Exam 4, 29 points -> 29 Exam 5, 28 points -> 28 Sub Total

112 points

Final Exam

25

Student Exam Total

137

Maximum possible points 165 Divide student total by Maximum possible points and multiply by 100 130 / 165 * 100 = 78.8% which rounds to 79% = B d. Round overs are as follows: • ###.50000000000000000 and higher rounds up to the next higher integer. • ###.49999999999999999 and lower rounds down to the next lower integer. • This policy will not be altered for any reason.

PGY 300 2020 Fall 6

August 13, 2020

e. The grading scale is as follows and will not change: Percent 90-100 87-89 81-86 77-80 73-76 70-72 60-69 50-59 0-49

Grade A AB+ B BC+ C D F

13) A grade of ‘I’ will be granted, subject to approval by the Course Coordinator, to students who meet ALL of the following requirements: a. A medical or family emergency that requires the student to be off campus for an extended period (i.e., more than one exam), and b. the student is passing the course with a C or better at the time of the request, and c. the student has taken more than the first three exams. 14) The terms of the incomplete will be determined by the Course Coordinator and must be satisfied within one calendar year of the end of the semester.

15) Students involved in academic dishonesty (cheating) will be subject to procedures listed in the Undergraduate Catalog.

16) Exam Schedule: Exam Number 1 2 3 4 5 6

Section Neurophysiology Cardiovascular Respiration Renal Gastrointestinal Endocrinology

Date 9/21 10/14 10/28 11/11 11/23 12/18 11:45am – 12:45 pm

Points 33 33 33 33 33 33

PGY 300 2020 Fall 7

August 13, 2020

1) Course Schedule

Section Neurophysiology Cardiovascular Respiration Renal GI Endocrinology

Instructor Slaughter Weil Hudson Hudson Hofmann Morales

Dates 08/31 – 9/18 09/23 – 10/09 10/14 - 10/23 10/28 – 11/06 11/11 - 11/20 11/25 – 12/06

Exam Date 9/21 10/14 10/28 11/11 11/25 12/18 (11:45am – 12:45pm)

Office hours via Zoom or Panopto are planed during the scheduled “class time” for this course (MWF starting at 1:50pm). The first five exams are scheduled for Mondays. If some issue (e.g., weather, technical problems, etc.) requires moving an exam to Wednesday or Friday, students must be available.

2) Learning objectives for each six sections of PGY 300: Section 1: Neurophysiology The overall objective of the following neurophysiology lecture sequence is to provide the student an understanding of the basic principles of neurophysiology and how these relate to health and disease. Topic 1: Understand the overall design of the nervous system Introduction to the components of the central nervous system Understand clinical approaches to evaluating nervous system function Topic 2: Learn the elements of the neuron and glia. Learn the electrical properties of neurons and how the membrane potential is formed. Topic 3: Understand the properties of the nerve cell membrane are detailed. Learn the function of membrane properties. Know the properties of membrane receptors and channels

PGY 300 2020 Fall 8

August 13, 2020 Topic 4: Learn the components of an action potential and how it is generated. Understand the properties of sodium and potassium channels and how they form the action potential. Understand the mechanisms that influence conduction speed and direction. Topic 5: Know the elements of the synapse. Understand the role of calcium in transmitter release Know the basic neurotransmitters used in the central and peripheral nervous system Topic 6: Learn how neurons interact to produce signals such as summation. Know the special properties of AMPA and NMDA channels and how they influence memory. Learn a model of memory developed from studies on Aplysia. Topic 7: Know the elements of sensory transduction. Learn the mechanisms associated with sensory system processing Understand the transduction mechanisms in olfaction, gustation, vision, and hearing. Topic 8: Learn the elements of skeletal muscle contraction. Describe how contraction is initiated. Understand neuronal control of muscle contraction at the neuromuscular junction. Topic 9: Understand the simple motor reflex. Learn how the muscle spindle influences muscle tone and contraction. Understand the function of the Golgi tendon organ. Learn the pathways of reciprocal inhibition and the crossed extension reflex. Topic 10: Learn the pathways of the autonomic nervous system. Understand the transmitter and receptor systems involved in the parasympathetic and sympathetic systems Learn the circuits of the enteric nervous system and how they interact with the parasympathetic and sympathetic systems.

PGY 300 2020 Fall 9

August 13, 2020 Section 2: Cardiovascular Physiology The overall objective of the following cardiovascular lecture sequence is to provide the student with an understanding of the basic principles of cardiovascular physiology and how these relate to health and disease. Key topics for each lecture are listed below and correspond to the subject material for each of the 33 questions that will be included on the exam. Topic 1: Introduction to Cardiovascular Physiology 1. Why do humans require a circulatory system? (Chapter 14) 2. What is the overall design of the cardiovascular system? (Chapter 14) 3. What are the main components of blood and what is their function within the cardiovascular system? (Chapter 16) Topic 2: Introduction to the Heart 4. What are the key anatomical structures of the heart? (Chapter 14) 5. What path does blood take through the heart’s four chambers and to the pulmonary and systemic circulations? (Chapter 14) 6. How is the heart’s electrical activity linked with mechanical activity to produce a coordinated pattern of contraction and relaxation? (Chapter 14) Topic 3: Electrical Activity of the Heart 7. How do action potentials differ between cardiac autorhythmic cells and cardiac contractile cells? (Chapter 14) 8. How are electrical signals conducted through the heart to initiate a coordinated mechanical contraction? (Chapter 14) 9. What aspects of the heart’s electrical activity are represented on an electrocardiogram? (Chapter 14) Topic 4: Mechanical Activity of the Heart 10. What are the mechanisms of excitation-contraction coupling in cardiac contractile cells? (Chapter 14) 11. What are the mechanical events of the cardiac cycle? (Chapter 14) 12. How are changes in pressure within each of the heart’s chambers linked with changes in blood volume within these chambers throughout each phase of the cardiac cycle? (Chapter 14) 13. How does the timing of the mechanical events of the cardiac cycle relate to the timing of the electrical events shown on an electrocardiogram? (Chapter 14)

PGY 300 2020 Fall 10

August 13, 2020 Topic 5: Regulation of Cardiac Function 14. What is cardiac output and what are its primary determinants? (Chapter 14) 15. How is heart rate determined? (Chapter 14) 16. What are the factors that influence stroke volume? (Chapter 14) 17. What is the “Frank-Starling Law of the Heart” and how does it link changes in venous return to changes in stroke volume? (Chapter 14) Topic 6: Vascular Function and Control of the Peripheral Circulation 18. What are the structural and functional properties of each of the five major types of blood vessels within the cardiovascular system? (Chapter 15) 19. What is the relationship between blood pressure, blood flow, and vascular resistance? (Chapter 15) 20. What are the determinants of blood pressure and how does blood pressure change as blood flows through the systemic circulation? (Chapter 15) 21. How is arteriolar resistance regulated and how do changes in arteriolar resistance influence blood pressure and the distribution of blood to various tissues? (Chapter 15) Topic 7: Autonomic Nervous System Control of the Heart and Circulation 22. How does the autonomic nervous system regulate heart rate and stroke volume? (Chapter 14) 23. How does the sympathetic branch of the autonomic nervous system influence arteriolar resistance and the distribution of blood flow throughout the body? (Chapter 15) 24. What is the baroreceptor reflex and how does it function to regulate arterial blood pressure? (Chapter 15) Topic 8: Exchange Function of the Microcirculation 25. What are the two types of capillaries and where is each type found throughout the body? (Chapter 15) 26. What are the mechanisms by which gases, fluids, electrolytes, and macromolecules move across the capillary endothelium? (Chapter 15) 27. How is capillary fluid exchange influenced by changes in fluid filtration and absorption? (Chapter 15) 28. What are the mechanisms by which alterations in capillary fluid exchange can lead to tissue edema? (Chapter 15)

PGY 300 2020 Fall 11

August 13, 2020 Topic 9: Cardiovascular Integration, Adaptation, and Pathophysiology 29. What adjustments are made by the cardiovascular system to provide sufficient oxygen delivery to active skeletal muscles during exercise? (Chapter 25) 30. What adjustments are made by the cardiovascular system during hypotension caused by an abrupt change in body posture or blood loss? (Chapter 15) 31. How can an electrocardiogram be used to detect abnormalities in cardiac electrical activity (i.e., arrhythmias)? (Chapter 14) 32. What are the causes and consequences of pathological alterations in cardiac mechanical activity (e.g., valve abnormalities or contractile dysfunction)? (Chapters 14 and 15) 33. What are the causes and consequences of atherosclerotic vascular disease and hypertension and how are these disorders commonly treated? (Chapter 15)

PGY 300 2020 Fall 12

August 13, 2020 Section 3: Respiratory Physiology The overall objective of the following respiratory lecture sequence is to provide the student an understanding of the basic principles of respiratory physiology and how these relate to health and disease. Topic 1: Organization of Respiratory System – Gas Laws The objective is to learn the anatomy of the respiratory system (skeletal, muscle, neurological, vascular and structural organization). The essential gas laws associated with respiration are also discussed, partial pressures, pressure gradients, and pressure volume relationships. Chapter 17. pgs. 570-578. Topic 2: Respiratory Mechanics The objective is to learn the mechanics of respiration; changes in alveolar pressure gradient, expansion of chest wall, pleural pressure relationship to structural and alveolar pressure changes. Lung compliance and elastance are discussed with relationship to disease. As well, surfactant production and function ...