Exam questions for apoptosis PDF

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Multiple-choice question (with answer) for the subject of apoptosis....

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Exam questions for apoptosis

1. Apoptosis is a highly regulated and controlled ______ process during an organism's lifecycle. A) biochemical B) biophysical C) necrotic D) physiological E) psychological 2. There are two major types of apoptosis pathways, the extrinsic and intrinsic pathways. In the extrinsic apoptosis pathway, the cells receive signals to start apoptosis from the outer environment. Which of the following is not the key component in the extrinsic apoptosis pathway? A) Caspase-8 B) Death receptor C) Mitochondria D) Both A and C E) Both B and C 3. Caspases are a family of protease enzymes playing essential roles in apoptosis and inflammation, which of the following caspase is involved in apoptosis? A) Caspase-1 B) Caspase-4 C) Caspase-5 D) Caspase-8 E) Caspase-13 4. Which of the following protein promotes apoptosis? A) BAX B) Bcl-2 C) c-FLIP D) Surviving E) XIAP 5. _______ is a disorder associated with overactive apoptosis; _______ is a disorder associated with defective apoptosis. A) Autoimmune diseases; Cancer B) Autoimmune diseases; Neurodegenerative disease C) Cancer; Autoimmune diseases D) Cancer; Neurodegenerative disease E) Neurodegenerative disease; Autoimmune diseases 6. Apoptotic and necrotic cells have very distinct morphological and biochemical characteristics. Which of the following statement is true regarding an apoptotic cell? A) Cell membrane destroyed B) Cell swelled and lysed

C) Chromatin condensed and DNA degraded D) Detrimental and can be fatal E) Inflammatory 7. There are two major types of apoptosis pathways, the extrinsic and intrinsic pathways. In the intrinsic apoptosis pathway, the cells receive signals to destroy itself from within. Which of the following is not the key component in the intrinsic apoptosis pathway? A) Apaf-1 B) Caspase-8 C) Caspase-9 D) Cytochrome C E) Mitochondria 8. Caspases are a family of protease enzymes playing essential roles in apoptosis. _______ is an initiator caspase while _____ is an effector caspase. A) caspase-3; caspase-7 B) caspase-3; caspase-8 C) caspase-6; caspase-3 D) caspase-8; caspase-3 E) caspase-8; caspase-9 9. Which of the following protein inhibits apoptosis? A) BAX B) Bcl-2 C) BID D) Cytochrome C E) SMAC 10. Which of the following is not released by the mitochondria? A) AIF B) Caspase-3 C) Cytochrome C D) Endonuclease G E) SMAC

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Answer: Question 1 = D Question 2 = C Question 3 = D Question 4 = A Question 5 = E Question 6 = C Question 7 = B Question 8 = D Question 9 = B Question 10 = B...