Pharm 4 Fun jacobson PDF

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VIRTUAL CLINICAL USE

Patient Education Worksheet-PHARM SHEET

Generic Name: raloxifene hydrochloride

Trade Name: Evista

Classification: HORMONE AND SYNTHETIC SUBSTITUTE; SELECTIVE ESTROGEN RECEPTOR ANTAGONIST/AGONIST

Therapeutic Use (Rationale for ordered medication): Indicated by increased bone mineral density, lowers serum total cholesterol and LDL cholesterol. Prevention and treatment of osteoporosis in postmenopausal women. Expected Pharmacological Action: Tamoxifen analog that exhibits selective estrogen receptor antagonist activity on uterus and breast tissue. Prevents tissue proliferation in both sites. Decreases bone resorption and increases bone density. Decreases serum total cholesterol and LDL cholesterol without lowering HDL cholesterol or triglycerides.

Medication Administration/ Correct Administration Techniques: PO once daily

Safe Dose Range/ Normal Dose Range: 60 mg PO once daily Contraindications/ Precautions/ Common Adverse Effects: Infection, flu-like syndrome, leg cramps, fever, arthralgia, myalgia, arthritis. Migraine headache, depression, insomnia. Hot flashes, chest pain, peripheral edema, decreased serum cholesterol. Nausea, dyspepsia, vomiting, flatulence, GI disorder, gastroenteritis, weight gain. Sinusitis, pharyngitis, cough, pneumonia, laryngitis. Rash, sweating. Vaginitis, UTI, cystitis, leukorrhea, endometrial disorder, breast pain, vaginal bleeding. Concomitant use of ESTROGENS not recommended; absorption reduced by cholestyramine.

Nursing Interventions/ Implications: Periodically monitor bone density, liver function, and plasma lipids; with concurrent oral anticoagulants, carefully monitor PT and INR. Monitor carefully for and immediately report S&S of thromboembolic events. Do not give drug concurrently with cholestyramine; however, if unavoidable, space the two drugs as widely as possible.

Evaluation of Medication Effectiveness: Periodically monitor bone density, liver function, and plasma lipids; with concurrent oral anticoagulants, carefully monitor PT and INR.

PATIENT EDUCATION WHILE TAKING MEDICATION  Contact physician immediately if unexplained calf pain or tenderness occurs.  Avoid prolonged restriction of movement during travel.  Drug does not prevent and may induce hot flashes.  Do not take drug with other estrogen-containing drugs.  Tell prescriber if you are taking drugs to lower your cholesterol.  Do not breast feed while taking this drug....